The MMP17 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to MMP17, and MT4MMP. This antibody recognizes Human, and Mouse antigen. The MMP17 Antibody (C-term) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. The protein encoded by this gene is
considered a member of the membrane-type MMP (MT-MMP) subfamily.
However, this protein is unique among the MT-MMP's in that it is a
GPI-anchored protein rather than a transmembrane protein. The
protein activates MMP-2 by cleavage